Plant Science

Biotalys Announces Strategic Refocus to Prioritize Lead Biocontrol Programs

Biotalys (Euronext: BTLS), a developer of protein-based biocontrol solutions, has announced a strategic partnership with 21st.BIO

Key Takeaways

  • Biotalys plans a strategic refocus to concentrate resources on its most advanced biocontrol assets.
  • The company expects to reduce total cash burn by approximately €20 million through 2028.
  • Lead biofungicide programs EVOCA NG and BioFun-6 will be prioritized.
  • Biotalys intends to reduce its workforce by 30 employees as part of the restructuring.
  • The company confirmed its cash runway extends into May 2026 and is exploring financing options.

Biotalys Refocuses Strategy on Core Biofungicide Portfolio

Biotalys (Euronext: BTLS), an Agricultural Technology company developing protein-based biocontrols for sustainable crop protection, announced its intention to proceed with a strategic refocus aimed at concentrating resources on its highest-priority programs while streamlining operations.

As part of the initiative, Biotalys plans to right-size its organizational structure and suspend certain early-stage activities to reduce operating expenses. The company stated that the measures are intended to preserve the long-term value of its technology platform while accelerating progress toward commercialization in markets with near-term potential.

The refocused strategy is expected to reduce total cash burn by an estimated €20 million through the end of 2028 compared to the company’s current operating structure.

“It is imperative that we deploy capital where it creates the greatest impact,” said Kevin Helash, Chief Executive Officer of Biotalys. “A narrowing of the focus to our core assets and most advanced programs aims to strengthen our ability to deliver innovative, sustainable crop protection solutions to growers.”


Biotalys Prioritizes Lead Programs and Key Partnerships

Focus on Advanced Biofungicides

Under the planned transition, Biotalys will prioritize development and regulatory advancement of its most advanced biofungicide programs, EVOCA NG and BioFun-6. The company will also continue supporting BioFun-7, developed in partnership with the Gates Foundation, and BioIns-2, its insecticide program partnered with Syngenta.

In parallel, Biotalys will maintain process development activities to achieve commercially competitive manufacturing costs. These efforts are supported by its recently announced strategic partnership with 21st.BIO. The company will also continue its collaboration with AgroFresh for post-harvest applications.

According to Biotalys, this partnership-driven approach is designed to reduce commercialization risk while maintaining momentum across priority programs.


Organizational Changes and Financial Outlook

As part of the refocused strategy, Biotalys announced its intention to reduce its workforce by 30 employees to better align costs with its streamlined portfolio. The company confirmed that its current cash runway extends into May 2026, consistent with previous disclosures.

Biotalys stated that it is in active discussions with investors regarding potential financing options to support the sharpened portfolio and long-term objectives.

“The intended measures should significantly reduce the investment required to deliver on Biotalys’ ambition of becoming a pioneer in Precision Biocontrols,” Helash added, noting the company’s focus on generating value for shareholders, stakeholders, and growers.


Biotalys Positions for Long-Term Value Creation

Through the strategic refocus, Biotalys aims to align capital allocation with its most mature assets while maintaining its broader technology platform. The company stated that the initiative is intended to strengthen its position in sustainable crop protection and support future value creation as regulatory and commercial milestones are achieved.

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