Crop Genomics

seqWell Launches AgriPrep™ Library Prep Kit To Support Scalable Low-Pass Genome Sequencing

seqWell announced the launch of the AgriPrep™ Library Prep Kit, expanding its next-generation TnX™ transposase product portfolio.
Image provided by seqWell.

Key Takeaways

  • seqWell launched the AgriPrep™ Library Prep Kit for agrigenomic sequencing workflows.
  • The kit supports low-pass whole genome sequencing and SKIM-sequencing approaches.
  • AgriPrep is designed for high-throughput, cost-efficient library preparation.
  • Early users reported workflow simplicity and cost savings in service lab settings.
  • seqWell will showcase AgriPrep at the Plant and Animal Genome Conference in January 2026.

seqWell Introduces AgriPrep™ Library Prep Kit

seqWell announced the launch of the AgriPrep™ Library Prep Kit, expanding its next-generation TnX™ transposase product portfolio. The company stated that AgriPrep is designed to facilitate broader adoption of low-pass whole genome sequencing (LP-WGS) and SKIM-sequencing approaches that deliver genome-wide insights at a lower cost than traditional whole genome sequencing.

According to seqWell, the new kit addresses scalability and cost barriers that have limited the use of genome-wide sequencing approaches in agrigenomics.


Workflow Design And High-Throughput Capability

AgriPrep is based on a tagmentation-driven library preparation method using seqWell’s one-step ExpressPlex workflow. The protocol requires approximately 100 minutes from start to finish, with around 30 minutes of hands-on time.

The company noted that the availability of up to 3,072 built-in indexes, combined with protocol simplicity and automation compatibility, enables ultra-high throughput workflows. seqWell said the kit is intended to support agrigenomic applications such as parentage analysis, genomic selection, trait mapping, and variant discovery.


seqWell Early Evaluation And Industry Feedback

Service Lab Validation And Cost Efficiency

Joris Parmentier, Associate Portfolio Director NGS at LGC Biosearch Technologies, said the AgriPrep method has been evaluated in the company’s next-generation sequencing service laboratory.

“We have been trialing the seqWell AgriPrep method in our NGS service lab for low-pass whole genome sequencing and have been impressed by the workflow simplicity and the resulting cost-savings,” Parmentier said. He added that the method shows potential for high-throughput workflows when combined with appropriate automation and compatible upstream and downstream technologies.

Jack Leonard, Co-Founder and Chief Technology Officer at seqWell, said early adoption by service providers and agricultural biotechnology companies reflects unmet demand for affordable and scalable library preparation solutions in agrigenomics. He noted that reducing library prep bottlenecks could support a broader shift from microarrays to low-pass whole genome sequencing.


Applications In Agrigenomics And Breeding Programs

seqWell stated that AgriPrep is designed to enable large-scale genotyping and genome-wide analysis at reduced cost, supporting more data-driven breeding and cultivation decisions. By simplifying library preparation, the company aims to expand access to sequencing-based approaches across agricultural research and commercial breeding programs.


seqWell To Highlight AgriPrep At PAG33

seqWell confirmed it will feature AgriPrep at the Plant and Animal Genome Conference (PAG33), taking place in San Diego from January 9 to 14, 2026.

Planned activities include an industry workshop titled The Long and Short of Scalable Low Pass Sequencing Workflows on Monday, January 12, from 4:00 PM to 6:00 PM, as well as presentations from early evaluators at organizations including HudsonAlpha Institute for Biotechnology, AgResearch, and SeqCenter. Additional sessions and posters will focus on scalable low-pass sequencing workflows and genotyping-by-sequencing applications using TnX™ transposase-based library preparation.

seqWell stated that these activities reflect its broader effort to support scalable, high-throughput sequencing solutions for agrigenomic research and commercial deployment.

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