PacBio & Corteva Develop High-Throughput Sequencing Workflows


PacBio’s collaboration with Corteva Agriscience represents a significant milestone in agricultural genomics. With the development of novel workflows that enable high throughput plant and microbial genome sequencing, the two companies are pushing the boundaries of what is possible in studying crop genetics and diversity. In addition, by using PacBio’s long-read sequencing technology, Corteva can sequence thousands of samples annually, opening up new possibilities for enhancing marker development and combatting pests and diseases at the molecular level.

The collaboration’s success has led to plans for further expansion into new application areas. With CRISPR-Cas gene editing and cutting-edge crop protection solutions, PacBio and Corteva are dedicated to revolutionizing agriculture by implementing seed product development tools. Biological insights gleaned from high-quality genomic data are critical in this endeavor. PacBio’s long-read sequencing technology provides the means for achieving these insights truly transformatively. The collaboration results were announced at the Advances in Genome Biology and Technology (AGBT) Agricultural meeting, underscoring this partnership’s significance in advancing the agricultural genomics field.

Balancing Benefits and Concerns: A Critical Analysis of Agricultural Genomics

Agricultural genomics has changed the field of agriculture by providing tools and techniques to enhance crop yield, increase nutritional value, and improve resistance to diseases, pests, and environmental stressors. By mapping and sequencing the genomes of various crops, researchers can identify valuable genes and incorporate them into breeding programs, developing new crop varieties with desirable traits. This approach has been precious in addressing global food security, as it helps develop crops capable of thriving in challenging conditions, such as drought or high-salinity soils. Additionally, agricultural genomics has the potential to reduce the environmental impact of farming by enabling more efficient resource utilization, targeted pesticide application, and reduced need for synthetic fertilizers.

Despite its many benefits, agricultural genomics also raises some concerns. One of the primary criticisms is that the widespread adoption of genetically modified organisms (GMOs) may lead to a loss of genetic diversity among crop species. As farmers increasingly rely on a smaller number of high-yielding, genetically modified varieties, the genetic pool may become more homogenous, which could increase the vulnerability of crops to pests, diseases, or environmental changes. Additionally, there are concerns surrounding the potential environmental consequences of GMOs, such as the unintended transfer of genetic traits to wild relatives, which could result in unforeseen ecological consequences. Lastly, the intellectual property rights associated with genomic technologies can lead to unequal access and benefit distribution, potentially exacerbating the agricultural sector’s existing social and economic disparities.

Photo by Yulian Alexeyev on Unsplash 

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