Key Takeaways:
- Profluent Bio and Corteva announce a strategic collaboration in AI-based protein and genome design
- Partnership integrates Profluent’s generative biology models with Corteva’s Catalyst and Genlytix™ platforms
- Focused on developing next-generation gene-editing tools for resilient, sustainable crops
- Collaboration aims to accelerate precision breeding and agricultural innovation globally
Profluent Bio and Corteva Join Forces to Accelerate Agricultural Innovation
Profluent Bio, a pioneer in generative AI for protein design, announced a strategic collaboration with Corteva, a global leader in agricultural sciences and solutions. The partnership combines artificial intelligence and gene editing to create a new generation of sustainable and resilient crops.
The collaboration, enabled through Corteva’s Catalyst platform, will leverage Profluent Bio’s expertise in generative biology and Corteva’s global research and development network. The companies will design targeted, AI-driven gene-editing solutions within Corteva’s Genlytix™ ecosystem, a suite of technologies supporting next-generation plant breeding and genome precision.
“This partnership shows the broad applicability of our AI design platform in generating functional biological sequences across industries,” said Ali Madani, CEO of Profluent Bio. “We’re thrilled to collaborate with Corteva, one of the world’s foremost agricultural innovators, whose leadership in plant science and field validation ensures advanced technologies make a real difference in agriculture. Our work with Corteva signals the abundance of opportunities ahead as AI unlocks breakthrough solutions to real challenges in biology.”
Combining AI, Gene Editing, and Field Expertise
Profluent Bio brings its advances in generative biology, including its foundation model, ProGen3—trained on a proprietary Protein Atlas of more than 80 billion protein sequences—and OpenCRISPR-1™, the first AI-created genome editor. By combining these tools with Corteva’s Genlytix™ ecosystem, the partnership aims to create an adaptive toolkit for precise crop engineering.
Corteva’s Genlytix™ platform supports a broad range of agricultural applications, from improved pest and drought resistance to enhanced yield and grain quality. The collaboration represents a convergence of AI-powered protein design and practical agricultural science, creating new potential for faster, more flexible development cycles in plant genetics.
“We’re excited to collaborate with Profluent as we work to develop next-generation solutions to address the new and growing challenges facing agriculture,” said Tom Greene, senior director at Corteva and global leader for Corteva Catalyst. “By combining our existing gene editing expertise with Profluent’s foundation models in protein design, we have the opportunity to engineer next-generation gene editing tools that improve precision, expand functionality, and create dependable solutions for growers worldwide.”
A Step Toward the Future of AI-Enabled Agriculture
Through this partnership, Profluent Bio and Corteva aim to redefine how genetic innovation is delivered to the field—accelerating the path from discovery to application. The collaboration underscores the growing importance of AI in agriculture, promising faster development of advanced genome editing tools that enhance crop sustainability and resilience while reducing reliance on traditional inputs.
By integrating deep learning, protein modeling, and field-scale validation, Profluent Bio’s collaboration with Corteva positions both organizations at the forefront of a new era in agricultural biotechnology.
