Key Takeaways
- T3Bioscience has secured its first international patent for RejuAgro, granted by Taiwan, expanding beyond the US patent the company received in 2023.
- RejuAgro is a natural metabolite derived from Pseudomonas species, operating via a novel mode of action that functions as both a bactericide and fungicide against crop pathogens.
- Initial target crops include apples (fire blight, apple scab), citrus (Huanglongbing, citrus canker), walnuts, grapes, and strawberries; EPA environmental toxicity testing was completed in late 2025.
- RejuAgro was developed through T3’s proprietary PROMISA extraction and screening platform, which the company expects to yield additional novel products in future.
- Next in the pipeline is RejuPrime, a plant biostimulant using the same core technology to support crop growth and yield under drought and salinity stress.
T3Bioscience Secures First International Patent for RejuAgro
T3Bioscience (T3), a US-based agricultural biologicals company focused on microbial solutions for bacterial and fungal crop pathogens, has announced that Taiwan has issued its first patent outside the United States for RejuAgro, the company’s lead product. The development extends an IP portfolio that began with a US patent granted in 2023, with further filings submitted globally since then.
RejuAgro is a naturally occurring metabolite produced by Pseudomonas species. T3 positions it as a dual-action bactericide and fungicide that operates through an entirely new mode of action — a distinction the company argues is critical in a crop protection market facing increasing pressure from antimicrobial resistance (AMR) and declining efficacy of older synthetic chemistries. The World Health Organization has designated AMR as one of the top global threats to public health and development, a designation that has intensified demand for effective alternatives within agricultural crop protection.
The PROMISA Platform Behind the Product
RejuAgro was developed through T3’s proprietary PROMISA technology, described as an extraction and screening platform built over multiple years to identify novel bioactive compounds from microbial sources. The company views PROMISA not only as the origin of RejuAgro but as the engine for a broader pipeline of future products.
“RejuAgro is a unique and stable bactericide and fungicide, but it is also a proof of concept for T3’s discovery platform PROMISA. PROMISA is T3’s proprietary extraction and screening technology that we developed over multiple years, and the platform that we anticipate will yield more novel products in the future,” said Dr. Ching-Hong Yang, Distinguished Professor at the University of Wisconsin-Milwaukee, who led the development of RejuAgro.
Mode of Action: Curative and Protective
A key claim for RejuAgro is that its novel mode of action delivers both curative and protective activity, meaning it can address existing infections as well as guard against new ones. Independent trials have reportedly demonstrated yield outcomes on par with conventional agrochemicals, while the nature-derived origin of the compound is intended to reduce the environmental and human health costs associated with synthetic inputs.
“Independent trials have proved that RejuAgro supports plant and yield growth on par with agrochemicals. The novel mode of action is also both curative and protective, allowing it to deliver unprecedented value in the field,” Yang said.
Target Crops and Regulatory Progress
T3 has identified the initial commercial targets for RejuAgro as apples, where the product addresses fire blight and apple scab; citrus, with a focus on Huanglongbing and citrus canker; and key diseases affecting walnuts, grapes, and strawberries. All EPA-required environmental toxicity tests were completed in late 2025 and are now being prepared for formal EPA submission, marking the next step toward US regulatory approval for the biopesticide.
T3Bioscience RejuPrime Next in the Pipeline
Beyond RejuAgro, T3 has disclosed the next product in development: RejuPrime, a plant biostimulant that draws on the same core PROMISA-derived technology to promote plant growth and yield performance under abiotic stress conditions, specifically drought and salinity. As climate variability continues to intensify pressure on agricultural systems, biostimulants targeting stress resilience represent a growing area of interest across the agtech sector.
